Student Theses and Dissertations
The Rockefeller University has awarded over one thousand Ph.D.s since 1959. This collection contains theses beginning with the graduating class of 2006. Earlier theses are added by request or as permission to digitize is received. For more information, visit the FAQ page.
2025
Identification and Characterization of Novel CRISPR-Cas Immune Effectors, Christian Fredrick Baca
Understanding of Intrinsic Sources of DNA Damage that Drive Human Disease: A Foray into the Study of DNA Interstrand Crosslinks and Genome-Embedded Ribonucleotides, Nicolas Johannes Georg Blobel
A Structural Perspective on Bacterial Transcription, Joshua John Brewer
The Evolution of Ribosome Assembly: Making Ribosomes in the Mitochondria, Chloe Burnside
Making Molecular Movies: Using Single-Molecule Techniques to Unveil Hidden Features of Protein-Chromatin Interactions, Gabriella N. L. Chua
Deriving Structural Insights About Mesoscale Chromatin Folding Using Coarse-Grained Oligonucleosome Modeling, Ariana Brenner Clerkin
Inquiries into the Mycobacterial Caseinolytic Protease System, Felipe Badke d'Andrea
Regulation of Chromatin Multi-Scale Organization and Function by Linker Histone H1, Irene Duba
Investigating the Double-Edged Sword of Rifampicin Resistance in Mycobacterium Tuberculosis, Kathryn A. Eckartt
Spontaneously Regenerative Corticospinal Neurons in Mice, Benjamin William Fait
Genome - Wide Regulatory Principles of Essential Transcription Factors from Mycobacterium Tuberculosis, Ruby Froom
Mechanisms of Telomere End Protection by TRF2, Audrey Goldfarb
Benchmarking Reinforcement Learning and Off Policy Evaluation for Medical Decision Making, Mason Hargrave
Serotonin-Mediated Sickness Behavior, Audrey Harnagel
Mechanisms and Evolution of Mitoribosomal Small Subunit Biogenesis, Nathan Harper
Aromatic Amino Acid Metabolome In The Human Gut Microbiota, David Chun-cheng Hsieh
A Neuronal Circuit Motif for Leaky Vector Integration, Abby Janke
Modulation of the CRISPR-Cas9 Immune Response, Hyejin Kim
How Clonal Ants Clone: The Reproductive Biology of the Clonal Raider Ant, Ooceraca Biroi, Kip D. Lacy
Exploring the Multifaceted Life of Beige Adipocytes, Zeran Lin
Mapping the Brain of the Clonal Raider Ant: Integrating Behavior, Neuroanatomy and Connectomics, Lindsey Etelvina Lopes
Hedgehog - like Proteins are Involved in a Novel Glia - Neuron Signalling Pathway in C. elegans, Elif Magemizoğlu
Investigation into the Neurogenetics of Vocal Learning in Tursiops Truncatus, the Bottlenose Dolphin, Brigid Maloney
Germline Genetic Modulator of Cancer Metastasis, Wenbin Mei
The Spatiotemporal Dynamics of Nomadic Behavior in the Clonal Raider Ant, Ooceraea Biroi, Dennis Octavio Melendez
A Scent of Direction: Exploring Adaptive Olfactory Navigation in Drosophila, Chad Morton
Recording Cellular Interactions in Germinal Centers and Beyond, Sandra Nakandakari-Higa
Serine Metabolism Leverages the Integrated Stress Response to Direct Stem Cell Fate During Tissue Regeneration, Jesse Stephen Swyer Novak
Molecular and Cellular Mechanisms of LIM Protein Mechanotransduction, Donovan Yong Zhi Phua
Nurture is Nature: The Molecular Basis of Caregiver Genotype Effects on Larval Growth and Caste Development in the Clonal Raider Ant, Patrick Konrad Piekarski
Decoding Dynamic Gene Regulation in Hair Cell Development and Regeneration, Caleb C. Reagor
Recovering from Dormancy: Fixation of CSM6-Inducing Spacers in the Bacterial Population, Amanda K. Shilton
Replicative Senescence is ATM-Driven, Reversible, and Delayed by Reduced ATM Activity at Low Oxygen, Alexander James Stuart
Sequential Transcriptional Gates in The Thalamo-Cortical Circuit Coordinate Memory Consolidation, Andrea Terceros
Neuromast Optogenetics Reveals Rules of Spatial Encoding in the Zebrafish Lateral Line, Nicolas Velez-Angel
Biochemical and Structural Insights into VCP Unfoldase and WRN Helicase Complexes, Lauren E. Vostal
Towards Models Mesoscale Chromatin Structure and Radiative DNA Damage via Computational Simulation, Devany Walsh West
Molecular and Metabolic Regulation of Gastrointestinal Cancer Metastasis, Norihiro Yamaguchi
ADP-Heptose and Nucleotide Enhancers Drive Fusobacteria-Induced Inflammation, Linzhi Ye
GPCR to Channel Communication in a Membrane Signaling Pathway, Yuxi Zhang
2024
Molecular Mechanisms of Sensing and Synergy by Anti-Bacteriophage Immune Systems in Staphylococcus, Dalton Van Banh
Investigating the Effect of Antibody-Mediated Feedback on Ongoing Germinal Center Responses, Alexandru Barbulescu
Breaking Down Microtubule Formation: Characterizing the Biochemical and Cellular Functions of the γ-Tubulin Ring Complex, Adi Y. Berman
On the Second Telomere Maintenance Machine: Structure, Recruitment, and Regulation of the CST–Polα/primase C-strand Fill-in Complex, Sarah Wang Cai
Structual Visualization of Cytoskeletal Force Tranduction, Ayala Carl
Revealing SMC5/6's Dynamic Behavior on Diverse DNA Topologies Through Single-Molecule Methods, Jeremy Tzu-Huai Chang
New Insights into the Evolution of Learned Vocalization from the Australian Zebra Finch, Taeniopygia castanotis, Matthew Henry Davenport
Cellular and Circuit Consequences of a Genetic Locus for Attention, Zachary Gershon
Cells that Kill: The Chemosensory Cell Types of Aedes aegypti Mosquitoes, Olivia Victoria Goldman
Recombination and Excision: DNA Repair Proteins in Prokaryotic Host-Virus Conflicts, Amer Azim Hossain
Using Small Molecule Tools to Study ATPase Mechanoenzymes, Natalie Jones
Vulnerability to G - Quadruplexes in BRCA2 - Null Medulloblastoma: A Protective Role for the PIF1 Helicase, Danielle L. Keahi
Proteomic Analysis of WNT Signaling and Metabolism of Fibrolamellar Hepatocellular Carcinoma, James Knox
A Platform for Analyzing Force Sensitivity and Multivalency in Actin Networks, Joseph Theo Levin
Single-Molecule Studies of CFTR Gating and Pharmacology, Jesper Bøegh Levring
Connecting Female Mating Decisions and Male Courtship Strategies in Drosophila, Rufei Li
Transcriptomic Signatures of Projection Class Neurons for Vocal Control, Stephanie Joy Marcus
RNA Therapeutics for Fibrolamellar Hepatocellular Carcinoma, Christoph Neumayer
Human Inborn Errors of Immunity: Tuberculosis, Autoimmunity, and Beyond, Masato Ogishi
Investigating the Supracellular Processes Underlying Emergent Material Phase Properties During Embryonic Skin Morphogenesis, Karl H. Palmquist
Elucidating the Role of Phospholipid Scramblase 1 in Antiviral Innate Immunity, Gabrielle Paniccia
Anterior Cingulate Function Across Multiple-Time Scales Shapes Learning and Memory, Josue Manuel Regalado
Structural Mechanisms of F-actin Mechanochemical Regulation and Flexible Network Assembly, Matthew J. Reynolds
Discovery and Optimization of a Family of Naturally Encoded Antibiotic Compounds that Evade Antibiotic, Adam Rosenzweig
Strain Variation as a Window Into the Neural Logic of Drosophila Mate Choice, Anna Ryba
Recall Germinal Center and Antibody Responses, Ariën Schiepers
Dissecting the Roles of Cancer Cell Lipid Metabolism in Tumor Progression and Immune Evasion, Mariluz Soula
Neural Mechanisms of Homeostatic Need and Reward, Bowen Tan
Use of Genetically Encoded Tools to Interrogate Mechanisms of Glutathione Homeostasis from Mitochondria to Mice, Rebecca Timson
Neural Population Dynamics Underlying Encoding of Time in the Cortico-Striatal Circuit, Francisca Martínez Traub
Influence of Mouse Motor Cortex on Vocal Musculature, César D. M. Vargas
The Nanomechanics of Protocadherin 15, A Protein Essential for Human Hearing, Camila M. Villasante
The Role of Gram - Negative Anaerobes in Hidradenitis Suppurativa, Samuel Clay Williams
Pioneer Factors Compete for Epigenetic Factors in Switching Stem Cell Fates, Yihao Yang
2023
A Gain-of-Function Role of Apolipoprotein E2 in Melanoma Progression, Nneoma Adaku
The Search for Regulatory Mutations in Gitelman Syndrome, Renan Eduardo Aparicio
Replaying Life's Tape With Intraclonal Germinal Center Evolution, Tatsuya Araki
Development of Improved Genetic Methods for Enterococcus Faecium, Victor Chen
Interrogation and Manipulation of the IGG FC Glycan, Aaron Keshav Gupta
Transgenic Tools in Ants and the Representation of Alarm Pheromones in the Ant Antennial Lobe, Taylor Eco Hart
Cortical Control of Naturalistic Facial Expression Production in Primates, Geena Rose Ianni
Neural Control of Sickness Behavior, Anoj Ilanges
Antibody-Effector Functions in Antiviral Response, Kevin Shuolong Kao
Using Chemical Probes to Examine Cellular Activities, Megan Elizabeth Kelley
Rarely Acquired Type II-A CRISPR-Cas Spacers Mediate Anti-Viral Immunity Through the Targeting of a Non-Canonical PAM Sequence, Claire T. Kenney
Sex Differences and the Evolution of Gene Expression, Samuel Khodursky
Neotelomere Formation by Telomerase in Human Cells, Charles Gunnar Kinzig
Multiplexed Mapping of the Interactome of G Protein-Coupled Receptors and Receptor Activity-Modifying Proteins, Ilana Beth Kotliar
Structures, Functions, and Druggability of the SARS-CoV-2 Replication–Transcription Complex, Brandon F. Malone
On the High-Dimensional Geometry of Neuronal Population Dynamics, Jason M. Manley
Bioorthogonal Tethering of Drug Fragments to Engineered G Protein-Coupled Receptors, Jordan M. Mattheisen
Mechanical Manipulation of Eukaryotic Chromatin by DNA-Binding Proteins, Tuan Nguyen
Structural and Functional Analysis of Substrate Recognition and Inhibition of the Multidrug Transporters MRP1 and MRP2, Harlan Linver Pietz
Converting an Allocentric Goal Direction into an Egocentric Steering Signal in Drosophila, Peter Mussells Pires